Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Population structure of eastern Sicily.

M Beretta, P Mazzetti, G Frosina

    Human Heredity
    |January 1, 1986
    PubMed
    Summary

    Genetic analysis of 11 red-cell enzymes in Eastern Sicily reveals population homogeneity with mainland Italy. High heterozygosity rates were observed but did not significantly correlate with interparental distance.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Phase II trial of 5-fluorouracil, leucovorin, interferon-alpha-2a, and cisplatin as neoadjuvant chemotherapy for locally advanced esophageal carcinoma.

    Cancer·1996
    Same author

    Intake of macronutrients and risk of breast cancer.

    Lancet (London, England)·1996
    Same author

    Increased circulating intercellular adhesion molecule-1 levels in type II diabetic patients: the possible role of metabolic control and oxidative stress.

    Metabolism: clinical and experimental·1996
    Same author

    Regional wall motion analysis by dobutamine stess echocardiography to distinguish between ischemic and nonischemic dilated cardiomyopathy.

    American heart journal·1996
    Same author

    Pleomorphic adenoma and adenoid-cystic carcinoma of salivary glands: immunohistochemical assessment of proliferative activity in comparison with flow-cytometric study.

    Cell proliferation·1996
    Same author

    The centromere as a target for the induction of chromosome damage in resting and proliferating mammalian cells: assessment of mitomycin C-induced genetic damage at kinetochores and centromeres by a micronucleus test in mouse splenocytes.

    Mutagenesis·1996

    Area of Science:

    • Human genetics
    • Population genetics
    • Biochemical genetics

    Background:

    • Red-cell enzymes are crucial genetic markers for population studies.
    • Understanding genetic diversity within and between populations is key to human evolutionary research.
    • Previous studies have established baseline genetic data for various Italian populations.

    Purpose of the Study:

    • To investigate the genetic variation of 11 red-cell enzymes in Eastern Sicily.
    • To compare allele frequencies with other Italian populations to assess genetic homogeneity.
    • To explore the relationship between heterozygosity and interparental distance.

    Main Methods:

    • Analysis of 11 red-cell enzyme systems (GLO, GPT, EsD, PGP, PGD, Dia, AcP, PGM, SOD, CAI, CAII).
    • Population sampling of 465 individuals from Eastern Sicily.
    • Statistical comparison of allele frequencies and heterozygosity rates.

    Main Results:

    • Eastern Sicily exhibits genetic homogeneity with mainland Italian populations for the studied enzyme systems.
    • A high overall heterozygosity rate of 0.77 was recorded.
    • No statistically significant correlation was found between heterozygosity and interparental distance.

    Conclusions:

    • The genetic profile of Eastern Sicilians aligns with that of mainland Italians for these red-cell enzymes.
    • The high heterozygosity suggests a complex demographic history or selective pressures.
    • Further research is needed to elucidate the factors influencing genetic variation and heterozygosity in this region.

    Related Experiment Videos