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A Highly Selective Fluorescent Chemosensor for Detecting Indium(III) with a Low Detection Limit and its Application
1Department of Fine Chem, Seoul National University of Science and Technology (SNUT), Seoul, 138-743, South Korea. chealkim@seoultech.ac.kr.
Journal of Fluorescence
|September 26, 2018
Summary
A novel chemosensor, BHC, offers highly selective and sensitive detection of indium(III) using a fluorescence turn-on method. This sensor achieves the lowest detection limit reported for fluorescent turn-on indium(III) chemosensors, demonstrating practical application potential.
Area of Science:
- Analytical Chemistry
- Materials Science
- Supramolecular Chemistry
Background:
- Development of selective and sensitive chemosensors is crucial for detecting metal ions.
- Indium(III) detection is important in various fields, including electronics and medicine.
- Fluorescence turn-on sensors offer advantages in signal-to-noise ratio and ease of use.
Purpose of the Study:
- To synthesize a novel chemosensor, BHC, for highly selective indium(III) detection.
- To investigate the fluorescence turn-on mechanism for indium(III) detection.
- To evaluate the sensor's performance, including its detection limit and practical applicability.
Main Methods:
- Synthesis of the BHC chemosensor ((E)-N-benzhydryl-2-((2-hydroxynaphthalen-1-yl)methylene)hydrazine-1-carbothioamide).
- Fluorescence spectroscopy for detecting indium(III) using a turn-on mechanism.
- Analytical techniques including ESI-mass spectrometry, Job plot analysis, and theoretical calculations to elucidate the detection mechanism.
- Application of the sensor in test strips for practical detection.
Main Results:
- The synthesized BHC chemosensor demonstrated high selectivity for indium(III).
- A fluorescence turn-on response was observed upon binding with indium(III).
- The sensor achieved a remarkably low detection limit of 0.89 μM, the lowest reported for fluorescent turn-on indium(III) chemosensors.
- The detection mechanism was confirmed to be the chelation-enhanced fluorescence (CHEF) effect.
- Successful application of BHC in test strips validated its practical utility.
Conclusions:
- The BHC chemosensor represents a significant advancement in the field of indium(III) detection.
- Its high sensitivity, selectivity, and practical applicability make it a promising tool for various analytical applications.
- The study provides valuable insights into the design and mechanism of fluorescent chemosensors for metal ion detection.
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