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Updated: Feb 4, 2026

A Protocol for Detecting and Scavenging Gas-phase Free Radicals in Mainstream Cigarette Smoke
Published on: January 2, 2012
Desacylghrelin but not acylghrelin is reduced during smoking cessation
Mahsa Ardeshiripur1, Mathias Rhein1, Helge Frieling1
1Department of Psychiatry, Socialpsychiatry and Psychotherapy, Center for Addiction Research (CARe), Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Abstract:
This study focused on the acetylation status of ghrelin examining acyl- and desacylghrelin and its effect on craving during 14 days of smoking abstinence. This is the first study demonstrating changes in desacylghrelin plasma levels in smokers compared to non-smokers while there was no difference of acylated ghrelin. Future studies should specifically refer to plasma ghrelin as either desacyl- or acylghrelin since both have different effects on tobacco-seeking behavior and the underlying physiology.
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