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[Cavinton Comforte in the correction of vascular cognitive disorders]

O A Shavlovskaya1, A B Lokshina1, D A Grishina1

  • 1Sechenov First Moscow State Medical University, Moscow, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|September 26, 2018
PubMed

Insights

Cavinton Comforte (CC) improved cognitive functions and fine motor skills in patients with chronic brain ischemia. This study highlights CC

Area of Science:

  • Neurology
  • Pharmacology

Background:

  • Chronic brain ischemia (HIGM) often leads to cognitive impairment and motor deficits.
  • Assessing therapeutic interventions for HIGM is crucial for improving patient outcomes.

Purpose of the Study:

  • To evaluate the efficacy of Cavinton Comforte (CC) in mitigating cognitive impairment and motor awkwardness in patients with HIGM.

Main Methods:

  • A study involving 30 patients (aged 50-65) diagnosed with HIGM and cognitive impairment.
  • Utilized standardized tests including MINI-Cog, Munsterberg, and TMT to assess cognitive function.
  • Patients received 10 mg of Cavinton Comforte (CC) three times daily for three months.

Main Results:

  • Significant improvements were observed in constructive praxis and short-term memory.
  • Enhanced visual search speed, visual-motor function, and attention selectivity.
  • Improved reproduction of visual images, perception, and motor task speed (drawing strokes).

Conclusions:

  • Cavinton Comforte (CC) demonstrated positive effects on cognitive functions.
  • The therapy also led to improvements in fine motor skills of the hands.
Abstract

Keywords:
cavinton comfortecerebrovascular diseasechronic brain ischemiacognitive disordersvinpocetine

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