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Testo and testo-Pt(II) bind DNA at different locations.

P Chanphai1, V Ouellette1, Sanat K Mandal2

  • 1Department of Chemistry-Biochemistry and Physics, University of Québec at Trois- Rivières C. P. 500, Trois-Rivières (Québec), G9A 5H7, Canada.

Chemico-Biological Interactions
|September 26, 2018
PubMed
Summary

New anticancer drugs, testo and testo-Pt(II), bind to DNA. Testo-Pt(II) forms more stable DNA adducts, indicating potential for targeted cancer therapy with reduced side effects.

Keywords:
ConjugationDNAMolecular modelingSpectroscopyTestoTesto-pt

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