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Vision: Microcircuits Rage against the Dimming of the Light
Benjamin Sivyer1, Henrique von Gersdorff2
1Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA.
Abstract:
At sundown when light levels fall, rod photoreceptors take the night shift from the daylight-sensitive cones and a specialized mammalian microcircuit 'wires' the rods into the ancestral cone pathway. A recent study combines serial electron microscopy and simultaneous patch clamp recordings to shed light on this microcircuit in unprecedented detail.
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