Related Experiment Video
Updated: Feb 4, 2026

Bacterial Detection & Identification Using Electrochemical Sensors
Published on: April 23, 2013
Phosphorus-doped graphene-based electrochemical sensor for sensitive detection of acetaminophen
Xuan Zhang1, Kai-Ping Wang2, Li-Na Zhang2
1College of Chemistry, Chemical Engineering & Biotechnology, Donghua University, Shanghai, 201620, China; Key Laboratory of Polar Materials and Devices, Ministry of Education, East China Normal University, Shanghai, 200241, China.
Abstract:
Phosphorus-doped graphene (P-RGO) was synthesized and employed as active electrode material to construct electrochemical sensor for acetaminophen (AP). The P-RGO coated glass carbon electrode (P-RGO/GCE) showed an excellent electrocatalytic activity for the oxidation of AP, resulted from highly enhanced electrochemical conductivity and accelerated electron transfer. The experimental conditions for AP detection were optimized, and under the optimal condition, a linear relationship between current intensity and concentration of AP was obtained in the range of 1.5-120 μM with a detection limit of 0.36 μM (S/N = 3). The developed sensor showed high selectivity for AP in the presence of various common species, excellent reproducibility and stability. The present sensor was also successfully applied for AP detection in pharmaceutical tablet samples.
More Related Videos
09:15Iridium Oxide-reduced Graphene Oxide Nanohybrid Thin Film Modified Screen-printed Electrodes as Disposable Electrochemical Paper Microfluidic pH Sensors
Published on: November 22, 2016
08:19Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
Published on: June 1, 2012
Related Concept Videos
What is an Electrochemical Gradient?
The chemical gradient relies on differences in the abundance of a substance on the outside versus the inside of a cell and flows from areas of high to low ion concentration. In contrast, the electrical gradient revolves around an...
The Phosphorus Cycle
Chirality at Nitrogen, Phosphorus, and Sulfur
A consequence of chirality is the need for enantiomeric resolution. While this is theoretically possible for all...
Interfacial Electrochemical Methods: Overview
Electrochemical Gradient and Channel Proteins: An Overview
The electrical gradient: The electrical gradient across cell membranes refers to the difference in electric charge between the inside and outside of a cell. This difference drives the movement of ions towards or away from the cells. For instance, if the inside of the cell is more negatively charged relative to...
Sensitivity, Specificity, and Predicted Value
Sensitivity is the...