Related Experiment Video
Updated: Feb 4, 2026
05:37
Experimental Model of Ligature-Induced Peri-Implantitis in Mice
Published on: May 17, 2024
3.3K
Titanium as a modifier of the peri-implant microbiome structure
Diane Daubert1, Alexander Pozhitkov2, Jeffrey McLean3,4
1Department of Periodontics, Clinical and Periodontal Research Laboratory, University of Washington, Seattle, WA (Washington), USA.
Clinical Implant Dentistry and Related Research
|September 27, 2018
Summary
Dissolved titanium products are linked to peri-implantitis and alter the peri-implant microbiome. This study investigated the relationship between titanium levels, microbiome changes, and peri-implantitis in patients with implants.
Area of Science:
- Dental Implantology
- Microbiome Research
- Biomaterials Science
Background:
- Accelerated titanium dissolution is implicated in peri-implantitis.
- The effect of titanium dissolution products on the peri-implant microbiome is unknown.
Purpose of the Study:
- To assess the relationship between the peri-implant microbiome, dissolved titanium levels, and peri-implantitis.
Main Methods:
- Collected clinical, microbiome (16S rRNA sequencing), and titanium data from 15 implants after 10 years in function.
- Analyzed plaque samples for titanium quantity using mass spectrometry.
- Clustered sequences using the QIIME pipeline.
Main Results:
- Peri-implantitis was associated with increased Veillonella; Streptococcus, Prevotella, and Haemophilus characterized health.
- Dissolved titanium was found in 40% of sites and linked to peri-implant disease (P=.02).
- Titanium levels correlated with microbiome composition and alpha-diversity, and significantly associated with microbiota composition (P=.045).
Conclusions:
- Titanium dissolution products are associated with peri-implantitis.
- These products may play a role in altering peri-implant microbiome structure and diversity.
More Related Videos
06:06Adjunctive Diode Laser Therapy and Probiotic Lactobacillus Therapy in the Treatment of Periodontitis and Peri-Implant Disease
Published on: May 9, 2022
3.1K
07:28Imaging Cell Viability on Non-transparent Scaffolds — Using the Example of a Novel Knitted Titanium Implant
Published on: September 7, 2016
11.9K
Related Concept Videos
03:38Structure of Lipids
98.9K
Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic...
98.9K
00:57Modified Boxplots
11.1K
A standard box and whisker plot informs us about the spread of the data in a given sample. One can identify the minimum value, maximum value, first quartile value, second quartile or median value, and third quartile.
However, the box plot does not tell the reader about outliers - values that lie far from the center of the data. We can modify the standard box and whisker plot to identify the outliers and visualize the actual spread of the data in a sample.
Initially, we calculate the adjusted...
However, the box plot does not tell the reader about outliers - values that lie far from the center of the data. We can modify the standard box and whisker plot to identify the outliers and visualize the actual spread of the data in a sample.
Initially, we calculate the adjusted...
11.1K
02:22Structures of Solids
17.8K
Solids in which the atoms, ions, or molecules are arranged in a definite repeating pattern are known as crystalline solids. Metals and ionic compounds typically form ordered, crystalline solids. A crystalline solid has a precise melting temperature because each atom or molecule of the same type is held in place with the same forces or energy. Amorphous solids or non-crystalline solids (or, sometimes, glasses) which lack an ordered internal structure and are randomly arranged. Substances that...
17.8K
02:34Structural Isomerism
21.7K
Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can...
Isomers are different chemical species that have the same chemical formula. Structural isomerism of coordination compounds can be divided into two subcategories, the linkage isomers and coordination-sphere isomers.
Linkage isomers occur when the coordination compound contains a ligand that can bind to the transition metal center through two different atoms. For example, the CN− ligand can bind through the carbon atom or through the nitrogen atom. Similarly, SCN− can...
21.7K
00:56Viral Structure
74.6K
Viruses are extraordinarily diverse in shape and size, but they all have several structural features in common. All viruses have a core that contains a DNA- or RNA-based genome. The core is surrounded by a protective coat of proteins called the capsid. The capsid is composed of subunits called capsomeres. The capsid and genome-containing core are together known as the nucleocapsid.
74.6K
01:10Antibody Structure
65.6K
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
65.6K