Related Experiment Video
Updated: Feb 4, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
Oxidative Status in Patients with Benign Paroxysmal Positional Vertigo
Ethem Şahin1, İldem Deveci2, Mehmet Emre Dinç3
1Department of Otolaryngology, Head and Neck Surgery, Bayındır Hospital İçerenköy, İstanbul, Turkey.
Oxidative stress may contribute to benign paroxysmal positional vertigo (BPPV). Patients with BPPV show altered thiol/disulfide homeostasis, indicating ongoing oxidative stress even after treatment.
Area of Science:
- Otorhinolaryngology
- Biochemistry
Background:
- Benign paroxysmal positional vertigo (BPPV) is a common cause of vertigo, particularly in older adults.
- BPPV symptoms arise from displaced otoconia within the semicircular canals.
Purpose of the Study:
- To investigate the potential role of oxidative stress in the etiology of BPPV.
- To utilize native thiol/disulfide (SH/SS) homeostasis as a novel biomarker for BPPV.
Main Methods:
- A prospective study involving 62 participants: 31 with BPPV and 31 healthy controls.
- Blood samples were analyzed to assess native thiol (SH) and disulfide (SS) levels, total thiol (TT), and their ratios.
Main Results:
- BPPV patients exhibited significantly lower SH levels and SH/TT ratios compared to controls.
- Patients with BPPV showed significantly higher SS/SH and SS/TT ratios, indicating increased oxidative stress.
- These oxidative stress markers remained altered even after successful BPPV treatment.
Conclusions:
- Oxidative stress appears to play a role in the development of BPPV.
- Mechanisms may involve calcium metabolism disturbances and direct cellular damage from free radicals.
- These findings suggest potential therapeutic targets related to managing oxidative stress in BPPV.
More Related Videos
10:21Evaluation of Hydration Status by Bioelectrical Impedance Vector Analysis in Patients with Ischemic Heart Disease Undergoing Exercise Stress Test
Published on: September 22, 2023
05:28Enucleation of the Prostate for the Treatment of Benign Prostatic Hyperplasia Using a 980 nm Diode Laser
Published on: May 5, 2020
Related Concept Videos
Reactions at the Benzylic Position: Oxidation and Reduction
Oxidation Numbers
Pyruvate Oxidation
First, the enzyme pyruvate dehydrogenase removes the carboxyl group from pyruvate and releases it as carbon dioxide. The stripped molecule is then oxidized and releases electrons, which are then picked up by NAD+...
Oxidation-Reduction Reactions
Marcia's Theory of Identity Status
Position-effect Variegation