Related Experiment Video
Updated: Feb 4, 2026

Murine Corneal Transplantation: A Model to Study the Most Common Form of Solid Organ Transplantation
Published on: November 17, 2014
A 15-Year Review of Corneal Transplant in Brazil
Hirlana Gomes Almeida1, Newton Kara-José, Richard Yudi Hida
1Department of Ophthalmology (H.G.A., N. Kara-José, R.Y.H., N. Kara-Junior), School of Medicine (Hospital das Clínicas of da Universidade de São Paulo- São Paulo- HC-USP), University of São Paulo, São Paulo, Brazil; and Department of Ophthalmology (R.Y.H.), Santa Casa de São Paulo, São Paulo, Brazil.
Purpose:
To analyze 15-year of corneal transplant in Brazil.
Methods:
Cross-sectional, retrospective, observational, and analytical study, between available data from the Brazilian Transplant Registry (January 2002-December 2016), collected by the Brazilian Association of Organ Transplantation was performed. The variables analyzed per year were number of corneal transplants, corneal transplants per million people (pmp), corneal transplant teams, and individuals on the waiting list for corneal transplants. Quantitative variables were expressed by their respective values. To verify the relationship of time with the variables, the Spearman correlation test was applied, adopting P<0.05 for rejection of the null hypothesis.
Results:
Evaluation of the data from 2002 to 2016 revealed an increase in number of (1) corneal transplants (4,976-14,534-approximately 292% in 15 years; P<0.0001); (2) corneal transplants pmp (29.4-71.1 pmp; P<0.0001); (3) productivity of corneal transplants teams (40.1-79 transplants by each team per year; P=0.067); (4) effectiveness in meeting the Brazilian population demand for corneal transplants per year (18.2%-57.0%; P<0.0001); (5) potential donors (P<0.0001), effective donors (P<0.0001), and nondonors (P<0.0001). There was a reduction in the number of patients on the waiting list (19,189-10,923; P=0.056).
Conclusion:
Despite the progress in the last decade, the number of corneal transplants in Brazil cannot meet the growing population demand. Thus, this study suggests the implementation of more effective public policies of corneal transplants in Brazil, to minimize disparities in national territory, adequately meet the population demand, and reduce the time in waiting lists for corneal transplants.
Related Concept Videos
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Other Nuclides: 31P, 19F, 15N NMR
While fluorine-19 and phosphorous-31 have high natural abundances (100%) and positive gyromagnetic ratios, nitrogen-15 has a low natural abundance and a negative gyromagnetic ratio. However, nitrogen-15 is still preferred over nitrogen-14 (which has a...
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...

