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A Perspective in Catalysis: Development of Efficient Methods in the Age of Sustainability
Matthew J O'Neill1, Josep Cornella2
1Max-Planck-Institut für Kohlenforschung Kaiser-Wilhelm-Platz 1 45470 Mülheim an der Ruhr, Germany.
Abstract:
Contemporary organic chemists have expended significant efforts in expanding the scope of sustainable methodologies in catalysis and synthesis. Our lab seeks to contribute to this goal by developing new methods that utilize cheap and abundant catalysts to provide solutions to persisting obstacles in the synthetic community, with simultaneous attentiveness to associated basic research. From this viewpoint, we will specifically address our work using nickel to control nucleophile isomerism, a work which led to the discovery of a catalytic Thorpe-Ingold effect, and other areas of interest that are being actively pursued. As observed throughout, these works made maximum effort to include an abundance of heterocycles and complex molecular motifs to further enhance the translational impact of these discoveries.
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