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Ocular progenitor cells and current applications in regenerative medicines - Review
K Gokuladhas1, N Sivapriya1, M Barath1
1World Stem Cell Clinic India LLP (ISO 9001:2015 Certified Clinic), #6, 9th Cross Street, Kapaleeshwar Nagar, Neelankarai, Chennai 600115, India.
Abstract:
The recent emerging field of regenerative medicine is to present solutions for chronic diseases which cannot be sufficiently repaired by the body's own mechanisms. Stem cells are undifferentiated biological cells and have the potential to develop into many different cell types in the body during early life and growth. Self renewal and totipotency are the characteristic features of stem cells and it holds a promising result for treating various diseases like diabetic foot ulcer, heart diseases, lung diseases, Autism, Skin diseases, arthritis including eye disease. Failure of complete recovery of eye diseases and complications that follow conventional treatments have shifted search to a new form of regenerative medicine using Stem cells. The ocular progenitor cells are remarkable in stem cell biology and replenishing degenerated cells despite being present in low quantity and quiescence in our body has a high therapeutic value. In this paper we have review the applications on ocular progenitor stem cells in treatment of human eye diseases and address the strategies that have been exploited in an effort to regain visual function in the advance treatment of stem cells without any side effects and also present the significance in advance stem cell research.
Insights
Stem cells offer promising regenerative medicine solutions for chronic diseases, including eye conditions. Ocular progenitor stem cells show high therapeutic value for restoring vision and treating eye diseases with advanced stem cell research.
Area of Science:
- Regenerative Medicine
- Ophthalmology
- Stem Cell Biology
Background:
- Chronic diseases often exceed the body's natural repair capabilities.
- Stem cells, with their self-renewal and totipotency, are key to regenerative medicine.
- Conventional treatments for eye diseases have limitations, necessitating novel approaches.
Purpose of the Study:
- To review the application of ocular progenitor stem cells in treating human eye diseases.
- To address strategies for regaining visual function using stem cell therapy.
- To highlight the significance of advanced stem cell research in ophthalmology.
Main Methods:
- Review of existing literature on ocular progenitor stem cells.
- Analysis of therapeutic strategies for stem cell-based eye treatments.
- Examination of research advancements in stem cell applications for visual restoration.
Main Results:
- Ocular progenitor stem cells possess significant therapeutic potential for degenerated eye conditions.
- Various strategies are being explored to leverage stem cells for visual function recovery.
- Advanced stem cell research offers potential for treating eye diseases with fewer side effects.
Conclusions:
- Stem cell therapy, particularly using ocular progenitor cells, represents a promising frontier in treating human eye diseases.
- Further research in advanced stem cell applications is crucial for overcoming limitations of conventional treatments and improving patient outcomes.
- Regenerative medicine using stem cells holds significant promise for restoring vision and addressing unmet needs in ophthalmology.
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