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Epithelial protein lost in neoplasm (EPLIN): Beyond a tumor suppressor

Daqing Wu1,2

  • 1Georgia Cancer Center and Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, USA.

Genes & Diseases
|September 28, 2018
PubMed
Summary

Epithelial protein lost in neoplasm (EPLIN) may suppress cancer metastasis. Downregulation of EPLIN is linked to tumor progression and clinical metastasis, highlighting its potential role in cancer therapy.

Keywords:
Actin cytoskeletonChemoresistanceEPLINEpithelial-to-mesenchymal transitionMetastasis suppressorTumor suppressor

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