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Published on: November 22, 2017
Influenza vaccination and prevention of antimicrobial resistance
Susanna Esposito1, Nicola Principi2,
1a Pediatric Clinic, Department of Surgical and Biomedical Sciences , Università degli Studi di Perugia , Perugia , Italy.
Introduction:
Abuse and misuse of available antimicrobial drugs have increased antimicrobial resistance (AMR), with relevant adverse health and economic impacts. Several factors suggest that the influenza vaccine is a possible effective measure to control AMR through a significant reduction in antibiotic consumption. In this paper, aspects related will be discussed.
Areas Covered:
Although the effectiveness of influenza immunization can significantly vary according to the study design, the circulating influenza viruses, the type of vaccine, the age of the enrolled subjects, the outcome measured and the season of the study, all experts agree that the influenza vaccine can significantly reduce the risk of contracting influenza in subjects of any age. Consequently, influenza vaccination may reduce the number of bacterial superimposed infections that can complicate influenza and require antibiotic prescriptions
Expert Commentary:
Several indirect and direct observations seem to indicate that influenza vaccines can play an important role in reducing influenza-related antibiotic prescriptions. This finding can lead to at least two undeniable advantages, reductions in drug expenditure and limitations of the risk of favoring AMR development. However, only when universal vaccination is accepted and implemented will the true advantages of the influenza vaccine in reducing AMR development be completely known and exploited.
Insights
Influenza vaccination can reduce antibiotic use by preventing infections and associated bacterial complications. This strategy is key to controlling antimicrobial resistance (AMR) and lowering healthcare costs.
Area of Science:
- Public Health
- Infectious Diseases
- Pharmacology
Background:
- Antimicrobial resistance (AMR) is a growing global threat driven by drug misuse.
- Antimicrobial drugs are frequently prescribed for influenza and its complications.
Purpose of the Study:
- To discuss the role of influenza vaccination in reducing antibiotic consumption.
- To explore the potential of influenza immunization as a strategy to combat AMR.
Main Methods:
- Review of existing literature and expert commentary on influenza vaccine effectiveness.
- Analysis of the link between influenza, antibiotic prescriptions, and AMR development.
Main Results:
- Influenza vaccination significantly reduces the risk of influenza illness across all age groups.
- Vaccination may decrease secondary bacterial infections, thereby lowering antibiotic prescriptions.
Conclusions:
- Influenza vaccines offer a viable approach to reduce antibiotic use and mitigate AMR.
- Widespread adoption of influenza vaccination can yield substantial public health and economic benefits by limiting AMR.
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