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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
Published on: May 21, 2017
11.9K
Transcatheter aortic valve replacement in low risk patients
Lucia Junquera1, Alfredo Ferreira-Neto1, Leonardo Guimaraes1
1Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada.
Minerva Cardioangiologica
|September 28, 2018
Summary
Transcatheter aortic valve replacement (TAVR) is becoming a preferred treatment for aortic stenosis, showing comparable results to surgery in intermediate-risk patients. Ongoing trials will determine its efficacy in low-risk individuals, potentially making TAVR the standard of care.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Technology
Background:
- Transcatheter aortic valve replacement (TAVR) has rapidly advanced, expanding from high-risk to lower-risk patient populations.
- Surgical aortic valve replacement (SAVR) has been the traditional treatment for severe aortic stenosis.
Purpose of the Study:
- To evaluate the expanding role and efficacy of TAVR in various patient risk groups, including low-risk individuals.
- To assess TAVR's comparability to SAVR and its potential to become the primary treatment for aortic stenosis.
Main Methods:
- Review of TAVR technology refinement and clinical experience.
- Analysis of observational, propensity-matched, and randomized trial data comparing TAVR and SAVR outcomes.
- Monitoring of ongoing randomized trials in low-risk patients.
Main Results:
- TAVR demonstrates results comparable to SAVR in intermediate-risk patients.
- Preliminary studies show promising outcomes for TAVR in low-risk populations.
- A small trial indicated TAVR's non-inferiority to SAVR for early and late outcomes up to six years.
Conclusions:
- TAVR is a viable and increasingly preferred option for severe aortic stenosis, even in lower-risk patients.
- Further research and ongoing trials are crucial to establish TAVR as the default treatment.
- Addressing valve durability and complications like conduction disturbances is key for TAVR's widespread adoption.
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