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Recent developments and highlights in rhinitis and allergen immunotherapy
Sietze Reitsma1, Soma Subramaniam2, Wytske W J Fokkens1
1Department of Otorhinolaryngology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Allergy
|September 28, 2018
Summary
This review covers recent advances in rhinitis, including allergic rhinitis (AR) and non-allergic rhinitis. It highlights progress in phenotyping, endotyping, and allergen immunotherapy (AIT) for personalized patient treatment.
Area of Science:
- Otorhinolaryngology
- Immunology
- Allergology
Background:
- Rhinitis, encompassing allergic (AR) and non-allergic forms, affects a significant portion of the population.
- Current treatment strategies for rhinitis require refinement for optimal patient outcomes.
- Allergen immunotherapy (AIT) presents a disease-modifying treatment option for allergic conditions.
Purpose of the Study:
- To provide a comprehensive overview of recent developments in allergic and non-allergic rhinitis.
- To discuss advancements in the phenotyping and endotyping of rhinitis for personalized treatment.
- To review current evidence and applications of allergen immunotherapy (AIT).
Main Methods:
- Literature review of recent publications on rhinitis and AIT.
- Synthesis of findings from original research papers, position papers, and guidelines.
- Analysis of evidence regarding AIT in various rhinitis subtypes.
Main Results:
- Recent advances in rhinitis phenotyping and endotyping facilitate tailored treatment approaches.
- Local allergic rhinitis is an area of growing research interest.
- Evidence supports the application of AIT in seasonal and perennial AR, local allergic rhinitis, and emerging applications.
Conclusions:
- Personalized medicine approaches, driven by phenotyping and endotyping, are advancing rhinitis care.
- Allergen immunotherapy (AIT) is a crucial therapeutic option with expanding applications in allergic rhinitis.
- Further research into novel AIT applications holds promise for improved rhinitis management.
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