Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The association of vitamin D deficiency with depressive disorders in patients with eating disorders: a cross-sectional study.

Journal of eating disorders·2026

Same author

Correction: Pneumococcal vaccination at 65 years and vaccination coverage in at-risk adults: A retrospective population-based study in France.

PloS one·2026

Same author

The mind-eat program leads to greater improvements in mindful, emotional, and external eating compared to intuitive eating-oriented education in adults with overweight or obesity: a randomized controlled trial.

The international journal of behavioral nutrition and physical activity·2026

Same author

Comparative accuracy of a predictive algorithm versus cardiologist assessment for 90-day readmission in decompensated chronic heart failure.

BMC cardiovascular disorders·2026

Same author

[Proposals from the French National Society of Internal Medicine on care pathways for patients with medical emergencies].

La Revue de medecine interne·2026

Same author

Severe hypertriglyceridemia induced by everolimus in a lung transplant patient: Case report.

Journal of clinical lipidology·2026

Same journal

Predictive analytics and risk stratification models in internal medicine: from risk scores to real-time machine learning.

Presse medicale (Paris, France : 1983)·2026

Same journal

Artificial Intelligence in skin disease therapeutics: from drug discovery to personalized treatment pathways.

Presse medicale (Paris, France : 1983)·2026

Same journal

AI in clinical diagnostics in dermatology: applications, validation, and real-world use cases.

Presse medicale (Paris, France : 1983)·2026

Same journal

Artificial Intelligence in medical research and publishing: progress, risks, and future perspectives.

Presse medicale (Paris, France : 1983)·2026

Same journal

Ethical, legal, and regulatory challenges in AI-based healthcare tools.

Presse medicale (Paris, France : 1983)·2026

Same journal

Decision-making for clinicians.

Presse medicale (Paris, France : 1983)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 4, 2026

The Rabbit Model of Accelerated Atherosclerosis: A Methodological Perspective of the Iliac Artery Balloon Injury

The Rabbit Model of Accelerated Atherosclerosis: A Methodological Perspective of the Iliac Artery Balloon Injury

Published on: October 3, 2017

Is hypertriglyceridemia atherogenic?

François Roubille¹, Ariane Sultan², Fabien Huet¹

¹Montpellier University Hospital, UFR de Médecine, Université Montpellier 1, Department of Cardiology, 371, avenue du Doyen-Gaston-Giraud, 34295 Montpellier cedex 5, France; Université de Montpellier, PhyMedExp, Inserm, CNRS, 34000 Montpellier, France.

Presse Medicale (Paris, France : 1983)

|September 29, 2018

Summary

This summary is machine-generated.

Triglycerides (TG) were once thought to be bystanders in cardiovascular disease (CVD). New research shows TG-rich lipoproteins play a causal role in CVD, suggesting new prevention strategies.

More Related Videos

Induction of Accelerated Atherosclerosis in Mice: The "Wire-Injury" Model

Induction of Accelerated Atherosclerosis in Mice: The "Wire-Injury" Model

Published on: August 25, 2020

Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice

Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice

Published on: September 26, 2018

Related Experiment Videos

Last Updated: Feb 4, 2026

The Rabbit Model of Accelerated Atherosclerosis: A Methodological Perspective of the Iliac Artery Balloon Injury

The Rabbit Model of Accelerated Atherosclerosis: A Methodological Perspective of the Iliac Artery Balloon Injury

Published on: October 3, 2017

Induction of Accelerated Atherosclerosis in Mice: The "Wire-Injury" Model

Induction of Accelerated Atherosclerosis in Mice: The "Wire-Injury" Model

Published on: August 25, 2020

Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice

Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice

Published on: September 26, 2018

Area of Science:

Cardiology
Metabolic Disorders
Lipid Metabolism

Background:

Atherosclerotic cardiovascular disease (ASCVD) reduction strategies primarily focus on low-density lipoprotein (LDL) reduction, mainly via statins.
Highly elevated triglycerides (TG) pose risks, including pancreatitis, and are linked to metabolic disorders, diabetes, alcohol consumption, and obesity.
Genetic factors contribute to severe cases of elevated TG.

Purpose of the Study:

To evaluate the role of triglycerides (TG) in the pathophysiology of cardiovascular diseases (CVD).
To explore emerging evidence supporting a causal link between TG and CVD.
To identify new therapeutic targets for cardiovascular risk management.

Main Methods:

Review of biological and basic research on TG-rich lipoproteins.
Analysis of recent epidemiological studies on TG and CVD.
Examination of genetic studies implicating TG in cardiovascular risk.

Main Results:

Biological and basic research indicate TG-rich lipoproteins are involved in CVD pathophysiology.
Epidemiological and genetic studies provide strong evidence for a causal role of TG in CVD.
TG are no longer considered mere bystanders in cardiovascular risk.

Conclusions:

Emerging evidence strongly supports a causal role for triglycerides in cardiovascular disease.
New approaches for patient management in primary and secondary CVD prevention are warranted.
Understanding TG's role opens avenues for novel therapeutic strategies in cardiovascular health.