Isolated Urethral Metastasis From a Primary Ovarian Malignancy

Area of Science:

• Gynecologic Oncology
• Medical Case Reports

Background:

• Epithelial ovarian cancer (EOC) is a leading cause of gynecologic cancer mortality.
• EOC commonly presents at advanced stages (3-4) with abdominopelvic metastases.
• Cutaneous metastases from EOC are exceptionally rare.

Observation:

• A 51-year-old patient with stage IIB EOC presented with an unusual recurrence.
• The recurrence manifested as an isolated metastasis in the external urethral meatus.
• This occurred two years after initial treatment with surgery and adjuvant chemotherapy.

Findings:

• This case represents a rare instance of isolated cutaneous metastasis of EOC.
• The location of the recurrence (external urethral meatus) is highly unusual.

Implications:

• Highlights the importance of thorough physical examinations during follow-up for EOC patients.
• Emphasizes the need for vigilance in detecting rare recurrence patterns, even with nonspecific symptoms.
• Suggests that clinicians and patients should consider a broader differential diagnosis for any new symptoms in EOC survivors.