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Updated: Feb 4, 2026

Light-Controlled Fermentations for Microbial Chemical and Protein Production
Published on: March 22, 2022
Beyond the Theoretical Yields of Dark-Fermentative Biohydrogen
Sanjay K S Patel1, Jung-Kul Lee1, Vipin C Kalia1
1Department of Chemical Engineering, Konkuk University, 1 Hwayang-Dong, Gwangjin-Gu, Seoul, 05029 Republic of Korea.
Abstract:
Theoretical hydrogen (H2) yield by dark fermentative route is 12 mol/mol of glucose. Biological H2 production yields of 3.8 mol/mol of glucose by microbes have been reported. Transient gene inactivation in combination with adaptive laboratory evolution strategy has enabled the H2 yield to exceed the stoichiometric production values.
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