Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inertial Frames of Reference01:03

Inertial Frames of Reference

8.8K
Newton’s first law is usually considered to be a statement about reference frames. It provides a method for identifying a special type of reference frame: the inertial reference frame. In principle, we can make the net force on a body zero. If its velocity relative to a given frame is constant, then that frame is said to be inertial. So, by definition, an inertial reference frame is a reference frame where Newton's first law holds valid. Newton's first law applies to objects with...
8.8K
Non-inertial Frames of Reference01:27

Non-inertial Frames of Reference

7.2K
A reference frame accelerating or decelerating relative to an inertial frame is a non-inertial frame. To help understand this, consider what taking off in an airplane, turning a corner in a car, riding a merry-go-round, and the circular motion of a tropical cyclone all have in common. All these systems are accelerating, decelerating, or rotating relative to the Earth; hence, they all are non-inertial frames. All these systems exhibit inertial forces, which merely seem to arise from motion,...
7.2K
Chemical Shift: Internal References and Solvent Effects01:17

Chemical Shift: Internal References and Solvent Effects

1.4K
In an NMR sample, precise measurement of the absolute absorption frequencies of nuclei is difficult. A standard internal reference compound is added, and the frequency difference between the reference signal and sample signals is measured.
The internal reference compound generally used in NMR spectroscopy is tetramethylsilane (TMS). TMS is preferred because it is chemically inert, soluble in NMR solvents, and easily removable. Also, the highly shielded methyl protons in TMS yield an intense...
1.4K
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

652
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
652
Physiology of Smell and Olfactory Pathway01:20

Physiology of Smell and Olfactory Pathway

12.9K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
12.9K
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

1.0K
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Brain Aging in Specific Phobia: An ENIGMA-Anxiety Mega-Analysis.

Human brain mapping·2026
Same author

Shared and specific associations of amygdala nuclei volumes with PTSD symptom domains and childhood trauma: An ENIGMA-PGC PTSD mega-analysis.

Molecular psychiatry·2026
Same author

Genome-wide association studies of infant and toddler temperament in European and multi-ancestry populations.

Nature human behaviour·2026
Same author

Regional, functional and transcriptomic decoding of multidimensional brain structure alterations in obsessive-compulsive disorder.

Nature communications·2026
Same author

Decomposing neuroanatomical heterogeneity in depression: insights from an ENIGMA major depressive disorder working group study in 5146 individuals.

Translational psychiatry·2026
Same authorSame journal

Motivational interviewing for substance use among adults in low- and middle-income countries: A systematic review.

The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa·2026
Same journal

A profile of psychotropic medication in bipolar patients of reproductive age.

The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa·2026
Same journal

Co-producing adult attention-deficit/hyperactivity disorder (ADHD) care in South Africa: A patient-centred framework for agency, trust, satisfaction and continuity.

The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa·2026
Same journal

Corrigendum: Locally relevant, ethically urgent: Defending SASOP's stance on transgender and non-binary youth.

The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa·2026
Same journal

Assessment of serum inflammatory cytokines in first-episode psychosis: Cross-sectional study.

The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa·2026
Same journal

Examining the length of hospital stay and associated factors in adult patients with schizophrenia.

The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa·2026
See all related articles

Related Experiment Video

Updated: Feb 4, 2026

Olfactory Assays for Mouse Models of Neurodegenerative Disease
07:27

Olfactory Assays for Mouse Models of Neurodegenerative Disease

Published on: August 25, 2014

22.6K

Sniffing out olfactory reference syndrome.

Eileen Thomas1, Juané Voges1, Bonginkosi Chiliza1

  • 1Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa.

The South African Journal of Psychiatry : SAJP : the Journal of the Society of Psychiatrists of South Africa
|September 29, 2018
PubMed
Summary
This summary is machine-generated.

Olfactory reference disorder (ORD) is a condition where individuals wrongly believe they emit unpleasant odors. A case study shows a multimodal treatment approach, combining medication and cognitive behavioral therapy, successfully treated a patient with this often-misdiagnosed condition.

More Related Videos

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome
08:31

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

Published on: July 31, 2016

14.5K
Electrophysiological Measurements from a Moth Olfactory System
06:16

Electrophysiological Measurements from a Moth Olfactory System

Published on: March 29, 2011

14.4K

Related Experiment Videos

Last Updated: Feb 4, 2026

Olfactory Assays for Mouse Models of Neurodegenerative Disease
07:27

Olfactory Assays for Mouse Models of Neurodegenerative Disease

Published on: August 25, 2014

22.6K
Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome
08:31

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

Published on: July 31, 2016

14.5K
Electrophysiological Measurements from a Moth Olfactory System
06:16

Electrophysiological Measurements from a Moth Olfactory System

Published on: March 29, 2011

14.4K

Area of Science:

  • Psychiatry
  • Psychology
  • Medical Case Study

Background:

  • Olfactory reference syndrome (ORS) involves the mistaken belief of emitting offensive body odor, causing distress and repetitive behaviors.
  • Concerns about body odor can be delusional, resisting reassurance, and ORS often goes unrecognized for years, leading to significant disability.
  • Poor insight in patients frequently hinders their willingness to seek psychiatric treatment.

Purpose of the Study:

  • To report a case of olfactory reference disorder (ORD) that required extensive medical interventions before diagnosis.
  • To highlight the challenges in diagnosing and treating ORD due to poor patient insight and misdiagnosis.
  • To demonstrate the efficacy of a multimodal treatment approach for ORD.

Main Methods:

  • Detailed case report of a patient with olfactory reference disorder (ORD).
  • Review of prior medical interventions and polysurgery undertaken by the patient.
  • Application of a multimodal treatment strategy including medication and cognitive behavioral therapy (CBT).

Main Results:

  • Accurate diagnosis of ORD was established after multiple unsuccessful medical interventions.
  • The patient experienced significant distress and disability due to the condition.
  • A multimodal treatment approach, including judicious medication and CBT within a therapeutic alliance, resulted in successful therapeutic outcomes.

Conclusions:

  • Olfactory reference disorder (ORD) is a challenging condition that can lead to significant disability and prolonged diagnostic delays.
  • A multimodal treatment strategy, integrating pharmacotherapy and psychotherapy (CBT), is effective for managing ORD.
  • Establishing a strong therapeutic alliance is crucial for successful treatment engagement in patients with ORD.