Related Experiment Video
Updated: Feb 4, 2026

The Cultivation, Growth, and Viability of Lactic Acid Bacteria: A Quality Control Perspective
Published on: June 16, 2022
Key role of peptidoglycan on acrylamide binding by lactic acid bacteria
Dan Zhang1, Wei Liu2, Liang Li1
11College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang, 150030 China.
Abstract:
The primary purpose of this study was to analyze the ability of four peptidoglycan (PGN) from different lactic acid bacteria to bind acrylamide (AA) and to identify the binding mechanism. In this study, to clarify the possible binding interactions among AA and components of PGN, chemical components, surface structure, amino acids component, and functional groups of peptidoglycans were studied. It was found that PGN from Lactobacillus plantarum 1.0065 had the highest ability to bind AA with 87%. Furthermore, a significant positive relation was found between the carbohydrate content of PGN and percentage of bind AA, and the content of four specific amino acids of PGN and AA binding ability were also positive correlated. Thereinto, alanine of PGN had a significant impact on AA binding among four amino acids. Additionally, the C-O (carboxyl, polysaccharides, and arene), C=O amide, and N-H amines groups of PGN were involved in AA binding.
Related Concept Videos
The Roles of Bacteria and Fungi in Plant Nutrition
Peptidoglycan Synthesis
Key Elements for Plant Nutrition
The Equilibrium Binding Constant and Binding Strength
Key Techniques in Microbiology
Conserved Binding Sites
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...

