Related Experiment Video
Updated: Feb 4, 2026
08:24
Choice and No-Choice Assays for Testing the Resistance of A. thaliana to Chewing Insects
Published on: May 14, 2008
17.6K
The choice for invasive prenatal tests after subfertility.
Manouk Hendrix1, Jolijn Arits1, Roy Bannink1
1Department of Obstetrics & Gynaecology, GROW School of Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Human Fertility (Cambridge, England)
|September 29, 2018
Summary
Women who conceived after fertility treatments are less likely to choose invasive prenatal testing (IPT). Maternal age, not fertility history, influences this decision for invasive prenatal testing.
Area of Science:
- Reproductive Medicine
- Prenatal Diagnostics
- Maternal-Fetal Medicine
Background:
- Subfertility affects a significant number of women seeking pregnancy.
- Invasive prenatal testing (IPT) offers diagnostic information but carries risks.
- Decisions regarding IPT can be influenced by various patient and clinical factors.
Purpose of the Study:
- To investigate if women conceiving after subfertility are less likely to undergo invasive prenatal testing (IPT).
- To identify factors influencing the decision to undergo IPT in this population.
- To compare IPT rates based on screening results (combined first trimester screening or second trimester screening) and advanced maternal age.
Main Methods:
- Retrospective study conducted at Maastricht University Medical Centre (MUMC+).
- Included 977 women who underwent IPT between January 2010 and December 2013.
- Analyzed IPT rates in relation to subfertility history, fertility investigations/treatment, and indications for testing (abnormal screening, advanced maternal age).
Main Results:
- Women conceiving after fertility investigations/treatment showed lower rates of IPT following abnormal second trimester screening (12.6% vs. 20.0%).
- This difference was not statistically significant after adjusting for maternal age and fetal anomaly severity.
- Maternal age was a significant factor in the decision for IPT, unlike fertility treatment or subfertility duration.
Conclusions:
- The reduced uptake of invasive prenatal testing in women conceiving after subfertility is influenced by the indication for testing and maternal age.
- Fertility history (type and duration of subfertility, or fertility treatments) appears to be a less significant factor in the decision for IPT.
- Further research may explore patient counseling strategies considering these influencing factors.
Related Concept Videos
01:20Mate Choice
11.8K
Mate choice—the decision about whom to mate with—is a type of natural selection, since animals must reproduce to pass down their genes. Mate choice is also called intersexual selection because the behavior occurs between the sexes.
11.8K
01:19Personal Choice and Fate Attributions
178
Some individuals interpret life events as a consequence of their personal choices and actions, while others believe that outcomes are dictated by fate or destiny. This divergence in perspective has been examined in psychological and cross-cultural studies, particularly in relation to religious faith and cultural beliefs about causality.Fate and Personal ResponsibilityPeople who emphasize personal responsibility view events as direct consequences of their decisions. For instance, breaking a leg...
178
01:10Factors Affecting α-Alkylation of Ketones: Choice of Base
3.6K
α-Alkylation of ketones is achieved in the presence of alkyl halides and a base. The reaction proceeds via the formation of an enolate ion followed by nucleophilic substitution. The choice of base employed is essential as it is the key factor in determining the reaction outcome.
The reaction involving bases like EtO− whose conjugate acid EtOH (pKa = 15.9) is stronger than the ketone (pKa = 19.2) results in an equilibrium mixture with higher ketone concentration. As a consequence,...
The reaction involving bases like EtO− whose conjugate acid EtOH (pKa = 15.9) is stronger than the ketone (pKa = 19.2) results in an equilibrium mixture with higher ketone concentration. As a consequence,...
3.6K
01:27Testes: Histology
3.0K
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
The spermatogenic cells, responsible for producing sperm, are...
3.0K
00:49Complementation Tests
6.3K
A complementation test is a simple cross to identify whether the two mutations are located on the same gene or different genes. It was first performed by Edward Lewis in the 1940s while working on fruit flies. He developed the test to identify the location and arrangement of different mutations on chromosomes.
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...
Organisms heterozygous for different mutations are crossed pairwise in all combinations. If present on different genes, the mutations can complement each other by providing the missing...
6.3K
01:04Significance Testing: Overview
12.7K
Significance testing is a set of statistical methods used to test whether a claim about a parameter is valid. In analytical chemistry, significance testing is used primarily to determine whether the difference between two values comes from determinate or random errors. The effect of a particular change in the measurement protocol, analyst, or sample itself can cause a deviation from the expected result. In the case of a suspected deviation/outlier, we need to be able to confirm mathematically...
12.7K