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Updated: Feb 4, 2026

Phage-Mediated Genetic Manipulation of the Lyme Disease Spirochete Borrelia burgdorferi
Published on: September 28, 2022
Treating Lyme carditis high-degree AV block using a temporary-permanent pacemaker
Chang Wang1, Sanoj Chacko1, Hoshiar Abdollah1
1Division of Cardiology, Kingston Health Science Center, Queen's University, Kingston, Ontario, Canada.
Abstract:
A 28-year-old previously healthy male presented with nonprodromal syncope and a 4-day history of chest pain, shortness of breath, and malaise. His ECG showed rapidly progressive high-degree AV block. His Suspicious Index in Lyme Carditis (SILC) score was 8, indicating high risk for Lyme carditis. Lyme serology revealed to be positive (anti-Lyme IgM). During the second day of hospitalization, the patient deteriorated his AV conduction, and a temporary-permanent pacemaker was implanted allowing ambulating in hospital the very same day. Temporary-permanent pacemakers for the management of transient high-degree heart block associated with Lyme carditis were only occasionally used in the past.
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