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Updated: Feb 4, 2026

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Butyric acid: Applications and recent advances in its bioproduction
Ling Jiang1, Hongxin Fu2, Hopen K Yang3
1School of Biology & Biological Engineering, South China University of Technology, Guangzhou 510006, China; College of Food Science and Light Industry, Nanjing Tech University, No. 5 Xinmofan Road, Nanjing 210009, China.
Abstract:
Butyric acid is an important C4 organic acid with broad applications. It is currently produced by chemosynthesis from petroleum-based feedstocks. However, the fermentative production of butyric acid from renewable feedstocks has received growing attention because of consumer demand for green products and natural ingredients in foods, pharmaceuticals, animal feed supplements, and cosmetics. In this review, strategies for improving microbial butyric acid production, including strain engineering and novel fermentation process development are discussed and compared regarding product yield, titer, purity and productivity. Future perspectives on strain and process improvements for butyric acid production are also discussed.
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