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Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative

Shao-Lin Zhang1, Zheng Yang1, Xiaohui Hu2

  • 1Cancer Centre, Faculty of Health Sciences, University of Macau, Taipa, Macau, China.

Bioorganic & Medicinal Chemistry Letters
|September 30, 2018
PubMed

Keywords:
Antiproliferative activityDichloroacetophenoneKinase inhibitionPyruvate dehydrogenase complexPyruvate dehydrogenase kinase

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