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Updated: Feb 4, 2026

Murine Fecal Isolation and Microbiota Transplantation
Published on: May 26, 2023
Nuts and Bolts of Fecal Microbiota Transplantation
Edward Krajicek1, Monika Fischer1, Jessica R Allegretti2
1Division of Gastroenterology, Indiana University, Indianapolis, Indiana.
Abstract:
Clostridium difficile infection (CDI) has become the leading cause of nosocomial infection in the United States with significant risk of both morbidity and mortality. While antimicrobial therapy forms the basis of treatment, there are several clinical scenarios in which antimicrobial therapy alone is insufficient. Evidence continues to show the safety and efficacy fecal microbiota transplantation (FMT) in recurrent and severe CDI. This review will outline FMT efficacy, safety, and indications and present practical advice for clinicians interested in best practices around delivery of FMT.
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