Related Experiment Video
Updated: Feb 4, 2026
06:10
Using Generative Art to Convey Past and Future Climate Transitions
Published on: March 31, 2023
1.5K
Pharmacovigilance in India: Present Scenario and Future Challenges
V Kalaiselvan1, Sushma Srivastava2, Abhishank Singh3
1Indian Pharmacopoeia Commission, Sector 23, Raj Nagar, Ghaziabad, 201002, India. vivekarts@gmail.com.
Drug Safety
|October 1, 2018
Summary
India
Area of Science:
- Pharmacovigilance and Drug Safety
- Public Health Surveillance
- Pharmaceutical Regulation
Background:
- India's formal adverse drug reaction (ADR) monitoring began in 1986.
- The Pharmacovigilance Programme of India (PvPI) was established in 2010, evolving from earlier initiatives.
- The program aims to ensure medicine benefits outweigh risks for the Indian population.
Purpose of the Study:
- To outline the evolution and current status of pharmacovigilance in India.
- To highlight achievements in establishing a robust drug safety monitoring system.
- To identify ongoing challenges and future directions for the PvPI.
Main Methods:
- Evolutionary analysis of pharmacovigilance initiatives in India.
- Description of the organizational structure, including the National Coordination Centre at the Indian Pharmacopoeia Commission (IPC).
- Overview of the PvPI's operational scope, including ADR reporting, training, and collaborations.
Main Results:
- Successful establishment of 250 adverse drug monitoring centers across India.
- PvPI designated as a WHO Collaborating Centre for Pharmacovigilance.
- Significant progress in fostering a culture of ADR reporting and enhancing patient safety.
Conclusions:
- The Indian pharmacovigilance system has made substantial progress but faces challenges.
- Key challenges include monitoring generic drugs, biosimilars, and specific drug classes.
- Continued efforts are needed for public awareness, counterfeit drug detection, and antimicrobial resistance surveillance.
Related Concept Videos
01:19Pharmacovigilance
1.7K
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.7K
01:43Sustainable Development
15.1K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.1K
00:59Tonicity in Animals
124.5K
The tonicity of a solution determines if a cell gains or loses water in that solution. The tonicity depends on the permeability of the cell membrane for different solutes and the concentration of nonpenetrating solutes in the solution within and outside of the cell. If a semipermeable membrane hinders the passage of some solutes but allows water to follow its concentration gradient, water moves from the side with low osmolarity (i.e., less solute) to the side with higher osmolarity (i.e.,...
124.5K
02:04Fixing Double-strand Breaks
14.8K
The double-stranded structure of DNA has two major advantages. First, it serves as a safe repository of genetic information where one strand serves as the back-up in case the other strand is damaged. Second, the double-helical structure can be wrapped around proteins called histones to form nucleosomes, which can then be tightly wound to form chromosomes. This way, DNA chains up to 2 inches long can be contained within microscopic structures in a cell. A double-stranded break not only damages...
14.8K
02:53Conservative Site-specific Recombination and Phase Variation
6.8K
Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
The recognition sites for Cre recombinase called LoxP...
6.8K
01:52Persuasion Strategies
43.5K
Researchers have tested many persuasion strategies, including the foot-in-the door and the door-in-the-face techniques, in a variety of contexts. Ultimately, the principles are effective in selling products and changing people’s attitude, ideas, and behaviors (Cialdini & Goldstein, 2004).
43.5K