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Chinese clinical practice guidelines for acute infectious diarrhea in children

Jie Chen1, Chao-Min Wan2, Si-Tang Gong3

  • 1Department of Gastroenterology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, 310051, China. hzcjie@zju.edu.cn.

World Journal of Pediatrics : WJP
|October 1, 2018
PubMed

Insights

Evidence-based guidelines for pediatric acute infectious diarrhea management in China recommend oral rehydration solutions for mild to moderate dehydration. Zinc supplements and specific probiotics are advised, while antibiotics are reserved for severe or specific cases.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Gastroenterology

Background:

  • Guidelines for managing acute infectious diarrhea in Chinese children were developed.
  • Focus on evidence-based indications for pediatric patient care.

Purpose of the Study:

  • To establish consensus on the management of acute infectious diarrhea in pediatric populations in China.
  • To provide evidence-based recommendations for clinicians.

Main Methods:

  • A systematic literature review was conducted up to June 2013.
  • Databases searched included PubMed, Cochrane, EMBASE, and Chinese biomedical databases.
  • Expert group discussions were used to formulate recommendations.

Main Results:

  • Hypotonic oral rehydration solutions (ORS) are recommended for mild to moderate dehydration.
  • Intravenous (IV) rehydration is advised for severe dehydration.
  • Zinc supplements, Saccharomyces boulardii, and Lactobacillus Rhamnus are recommended for acute infectious diarrhea.
  • Lactose-free diets can shorten diarrhea duration.
  • Antibiotics are recommended only for specific conditions like dysenteric diarrhea or severe cholera.

Conclusions:

  • Consensus was reached on controversial treatment principles for acute infectious diarrhea in China.
  • The guidelines provide a framework for pediatric infectious diarrhea management.
Abstract

Keywords:
ChildrenDehydrationDiarrheaInfectionProbioticsRehydrationTreatment

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