Mapping visuospatial and self-motion perception functions in the left parietal lobe.

Area of Science:

• Neuroscience
• Neurosurgery
• Neuroanatomy

Background:

• The parietal lobe is crucial for somatosensation, language, calculation, and visuospatial processing.
• Low-grade glioma resection requires precise surgical planning to preserve critical brain functions.
• Intraoperative mapping is essential for defining functional boundaries during brain tumor surgery.

Observation:

• This video showcases intraoperative mapping of the left parietal lobe during a low-grade glioma resection.
• Standard sensory and language mapping techniques were employed.
• The "Line Bisection" task revealed ipsilateral spatial neglect upon subcortical stimulation of the gyrus angularis.

Findings:

• Subcortical stimulation of the gyrus angularis was associated with ipsilateral spatial neglect, a phenomenon typically observed in the right parietal lobe.
• Stimulation at a more posterior site elicited vertigo, likely due to involvement of the superior longitudinal fasciculus.
• These intraoperative findings were instrumental in delineating the functional limits for safe glioma resection.

Implications:

• The study expands the understanding of left parietal lobe functional organization and potential deficits.
• It demonstrates the utility of specific tasks like "Line Bisection" for intraoperative neuro导航.
• Precise functional mapping aids in optimizing surgical outcomes and minimizing postoperative neurological deficits in parietal lobe tumor resections.