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The burden of pediatric status epilepticus: Epidemiology, morbidity, mortality, and costs

Kevin Gurcharran1, Zachary M Grinspan2

  • 1Department of Pediatrics, Weill Cornell Medicine, New York, NY, United States; New-York Presbyterian Hospital, New York, NY, United States.

Seizure
|October 2, 2018
PubMed

Insights

Status epilepticus (SE) affects about 20 in 100,000 children annually, with a 3% mortality rate. Prompt treatment is crucial to minimize significant pediatric SE morbidity, mortality, and costs.

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Public Health

Background:

  • Status epilepticus (SE) is a critical neurologic emergency in children.
  • Understanding its epidemiology, outcomes, and economic impact is vital for effective management.

Purpose of the Study:

  • To provide a comprehensive summary of the epidemiology, morbidity, mortality, and costs associated with pediatric status epilepticus.
  • To highlight key risk factors and outcomes related to SE in children.

Main Methods:

  • A thorough review of existing medical literature was conducted.
  • Data on incidence, mortality, etiology, recurrence, and costs were synthesized.

Main Results:

  • Pediatric SE incidence is approximately 20 per 100,000 children yearly, with a 3% mortality rate.
  • Symptomatic etiologies are linked to poorer outcomes; febrile SE is the most common cause in early childhood.
  • Recurrence risk after a first SE episode is 25-40%, and costs range from $10,000 to over $100,000 per episode.

Conclusions:

  • Status epilepticus is a significant pediatric neurologic emergency.
  • Etiology plays a critical role in SE-related morbidity, mortality, and cost.
  • Timely and effective treatment is essential to mitigate adverse outcomes.
Abstract

Keywords:
EpidemiologyMortalityPediatricsReviewStatus epilepticus

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