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Related Concept Videos

Blind Procedures02:07

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Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
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Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
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Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
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Related Experiment Video

Updated: Feb 4, 2026

Experience is Instrumental in Tuning a Link Between Language and Cognition: Evidence from 6- to 7- Month-Old Infants' Object Categorization
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Experience is Instrumental in Tuning a Link Between Language and Cognition: Evidence from 6- to 7- Month-Old Infants' Object Categorization

Published on: April 19, 2017

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Blinding: Linking Evidence to Practice.

Steven J Kamper

    The Journal of Orthopaedic and Sports Physical Therapy
    |October 2, 2018
    PubMed
    Summary

    Blinding in clinical trials, particularly those relevant to physical therapists, is crucial for minimizing bias. The level of risk from unblinded trials depends on the intervention and outcome measures used.

    Area of Science:

    • Clinical trial methodology
    • Evidence-based physical therapy

    Background:

    • Blinding is a critical component of rigorous clinical research.
    • Unlike clinical practice, blinding is not routinely used in daily patient care.
    • Its importance in research, especially for physical therapy trials, warrants careful consideration.

    Purpose of the Study:

    • To explore the significance of blinding in clinical trials.
    • To discuss the complexities of blinding in the context of physical therapy research.
    • To examine the potential for bias in trials lacking blinding.

    Main Methods:

    • This is a conceptual discussion and critical review of blinding in clinical trials.
    • Focuses on the implications for physical therapy research and practice.
    • Considers the influence of intervention types and outcome measures on bias risk.
    Keywords:
    biasblindingclinical practiceevidence-based practiceresearch

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    Main Results:

    • Trials without blinding (participants, therapists, assessors) are susceptible to bias.
    • The magnitude of bias risk is not uniform and varies based on study specifics.
    • The impact of blinding is context-dependent, influenced by intervention and outcome nature.

    Conclusions:

    • Blinding is essential for enhancing the internal validity of clinical trials.
    • Physical therapists must critically evaluate the potential for bias in unblinded studies.
    • Understanding the nuances of blinding is key to interpreting research findings accurately.