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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
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Evaluation of Left Ventricular Structure and Function using 3D Echocardiography

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Treatment outcomes and therapeutic evaluations of patients with left ventricular aneurysm

Yonggang Sui1, Siyong Teng1, Jie Qian1

  • 1Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, People's Republic of China.

The Journal of International Medical Research
|October 2, 2018
PubMed

Insights

Surgery, specifically coronary artery bypass grafting (CABG) with left ventricular resection, is recommended for left ventricular aneurysm (LVA). This surgical approach showed improved outcomes compared to drug treatment or percutaneous coronary intervention (PCI).

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Interventional Cardiology

Background:

  • Left ventricular aneurysm (LVA) is a serious cardiac condition.
  • Effective treatment strategies for LVA are crucial for improving patient outcomes.

Purpose of the Study:

  • To compare the efficacy of three LVA treatments: CABG with resection, drug therapy, and PCI.
  • To evaluate clinical characteristics and survival rates across treatment groups.

Main Methods:

  • 183 LVA patients were divided into three groups: CABG-resection (51), drug treatment (65), and PCI (67).
  • Clinical data and survival rates were analyzed and compared.
  • Postoperative left ventricular dimensions and ejection fraction were assessed.

Main Results:

  • All treatment groups showed improvement in left ventricular function post-surgery.
  • The CABG-resection group demonstrated better left ventricular ejection fraction (LVEF) and left ventricular end-diastolic dimension (LVEDD) compared to other groups.
  • Higher survival and non-recurrence rates were observed in the CABG-resection group, though not statistically significant.

Conclusions:

  • Surgical intervention, particularly CABG with left ventricular resection, is the preferred initial treatment for LVA.
  • Conservative management may be suitable for select patients.
  • CABG with resection offers potential advantages in LVEF, LVEDD, survival, and non-recurrence rates over PCI and drug therapy.
Abstract

Keywords:
Left ventricular aneurysmcoronary artery bypass graftingleft ventricular ejection fractionleft ventricular end-diastolic dimensionleft ventricular resectionpercutaneous coronary intervention

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