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Scalable Synthesis of Multivalent Macromonomers for ROMP
Hung V-T Nguyen1, Nolan M Gallagher1, Farrukh Vohidov1
1Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States.
ACS Macro Letters
|October 2, 2018
Summary
Researchers developed a rapid synthesis for functional monomers, enabling diverse branched macromonomers for ring-opening metathesis polymerization (ROMP). This advances the creation of complex nanostructured polymers.
Area of Science:
- Polymer Chemistry
- Macromolecular Science
Background:
- Direct synthesis of functional polymers avoids complex post-modification steps.
- Monomer synthesis is a key challenge for creating functional polymers.
- Living polymerization techniques require readily available functional monomers.
Purpose of the Study:
- To develop a rapid and versatile method for synthesizing functional monomers.
- To create diversely functionalized branched macromonomers for ring-opening metathesis polymerization (ROMP).
- To expand the accessibility of complex nanostructured macromolecules.
Main Methods:
- A three-step convergent synthesis of a divalent exo-norbornene imide monomer.
- Iterative procedures for synthesizing tri- and tetra-valent branched macromonomers.
- Utilizing the synthesized macromonomers in ROMP.
Main Results:
- Successfully synthesized divalent, tri-valent, and tetra-valent branched macromonomers.
- Demonstrated efficient coupling of the monomer with nucleophiles and azides.
- Produced Janus bottlebrush block copolymers and bottlebrush polymers with multiple conjugated small molecules.
Conclusions:
- This method significantly enhances the scalability and diversity of functional polymers synthesized via ROMP.
- The developed branched macromonomers are versatile building blocks for advanced polymer architectures.
- The approach simplifies the creation of complex nanostructures for various applications.
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