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The role of Tsukushi (TSK), a small leucine-rich repeat proteoglycan, in bone growth

Kosei Yano1,2, Kaoru Washio2, Yuka Tsumanuma1

  • 1Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

Regenerative Therapy
|October 2, 2018
PubMed
Abstract

Keywords:
BMP, bone morphogenetic proteinChondrocyteECM, extracellular matrixEDTA, ethylenediaminetetraacetic AcidEndochondral ossificationFBS, fetal bovine serumFGF, fibroblast growth factorGrowth plateITS, insulin-transferrin-selenium supplementsSLRP, small leucine-rich repeat proteoglycanSLRPsSkeletal developmentTGF, transforming growth factorTRAP, tartrate-resistant acid phosphataseTSK, TsukushiTsukushiWT, wild typeβ-gal, β-Galactosidase

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