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Related Concept Videos

Communication01:03

Communication

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Communication between two animals occurs when one animal transmits an information signal that causes a change in the animal that receives the information. Organisms communicate with one another in a host of different ways. Signals can be auditory, chemical, visual, tactile, or a combination of these. Communication is a critical behavioral adaptation that promotes survival, growth, and reproduction.
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Communication01:28

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Sharing information, concepts, and emotions to foster mutual understanding is communication. The sender, recipient, and transaction must be considered in this manner. The sender is the person who shares the message, the recipient is the person who receives and understands the message, and the transaction is the method used to deliver the message and the variables that affect the communication's context and surroundings. The nurse-client connection is built on therapeutic communication.
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A Microfluidic Device for Quantifying Bacterial Chemotaxis in Stable Concentration Gradients
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Controlled communication between physically separated bacterial populations in a microfluidic device.

Ekaterina Osmekhina1, Christopher Jonkergouw1, Georg Schmidt1

  • 1Department of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, 02150, Espoo, Finland.

Communications Biology
|October 2, 2018
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Summary
This summary is machine-generated.

Engineered microbial communities can now coexist and function independently using a novel microfluidic system. This setup allows communication via quorum sensing, enabling stable, long-term control of microbial interactions for complex genetic regulation.

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Area of Science:

  • Synthetic biology
  • Microfluidics
  • Microbial community engineering

Background:

  • Microbial systems engineering aims to create co-existing and co-functioning populations.
  • Specialized functions within microbial consortia can be achieved through engineered interactions.

Purpose of the Study:

  • To develop a microfluidic system for independent growth and communication of distinct microbial populations.
  • To demonstrate the use of quorum-sensing signaling for stable coupling and control of microbial communities.

Main Methods:

  • Utilized a microfluidic device enabling long-term, separate cultivation of microbial populations.
  • Implemented a nano-cellulose filter for controlled communication between populations.
  • Employed quorum-sensing signaling to couple microbial consortia.

Main Results:

  • Achieved independent growth of distinct microbial populations within the microfluidic system.
  • Established rapid and stable communication between coupled populations over extended periods.
  • Demonstrated the ability to drive nonlinear responses through controlled microbial communication.

Conclusions:

  • The developed microfluidic system facilitates standardized, context-independent interaction between microbial populations.
  • This approach provides a foundation for constructing complex, community-wide dynamic genetic regulatory mechanisms.
  • Engineered microbial communities with controlled communication open new avenues in synthetic biology.