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Establishing the Genomic Knowledge Matrix for Nursing Science.

Mary Regan1, Mary B Engler2, Bernice Coleman3

  • 1Chi, Associate Professor, University of Maryland School of Nursing, Baltimore, MD, USA.

Journal of Nursing Scholarship : an Official Publication of Sigma Theta Tau International Honor Society of Nursing
|October 2, 2018
PubMed
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The Genomic Knowledge Matrix guides nurse scientists in integrating omics into research. It outlines essential knowledge in cellular biology, physiology, microbiology, and bioinformatics for advancing genomic nursing science.

Keywords:
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Area of Science:

  • Genomic Nursing Science
  • Bioinformatics
  • Translational Science

Background:

  • Nursing research requires integration of multiple omics disciplines.
  • The Genomic Nursing Science Blueprint outlines key research recommendations.
  • Existing genomic competencies need expansion to encompass diverse omics fields.

Purpose of the Study:

  • To establish the necessary knowledge base for integrating omics into nursing research.
  • To accelerate the achievement of recommendations from the Genomic Nursing Science Blueprint.
  • To develop a framework for understanding omics in the context of nursing science.

Main Methods:

  • The Genomic Knowledge Matrix was developed in three phases.
  • Phase 1 involved an evidence, bioinformatics, and technology review by the ONSEN Education Workgroup.
  • Phases 2 and 3 included expert review, revisions by the ONSEN Advisory Panel, and public comment.

Main Results:

  • The Matrix identifies key content areas: cellular and molecular biology, system physiology, microbiology, and translational bioinformatics.
  • It defines minimum required preparation for nurse scientists to understand and integrate omics.
  • Variable levels of understanding are established based on the nurse scientist's role.

Conclusions:

  • The Genomic Knowledge Matrix provides essential guidance for nurse scientists integrating genomics into research.
  • It details critical knowledge elements for understanding omics in health and disease.
  • The Matrix offers flexible guidance for fundamental genomic content in nursing curricula.