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Mastocytosis.

Cathy S Birn1

  • 1Cathy S. Birn, MA, RN, CGRN, CNOR, is Pre-Procedure Assessment Coordinator, Endoscopy, Memorial Sloan-Kettering Cancer Center, New York.

Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates
|October 2, 2018
PubMed
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Mastocytosis, a rare disorder of mast cell proliferation, frequently causes significant gastrointestinal symptoms. Gastroenterology nurses must recognize these common digestive issues in patients with mastocytosis.

Area of Science:

  • Gastroenterology
  • Hematology
  • Oncology

Background:

  • Mastocytosis is a rare disorder involving abnormal mast cell accumulation in various body tissues.
  • Gastrointestinal (GI) manifestations are highly prevalent, affecting 70%-80% of patients with mastocytosis.
  • Symptoms range from mild to life-threatening, impacting daily life.

Purpose of the Study:

  • To highlight the significant gastrointestinal manifestations of mastocytosis.
  • To emphasize the importance of recognizing these symptoms in clinical practice.
  • To inform gastroenterology nurses about this underdiagnosed condition.

Main Methods:

  • Review of existing literature on mastocytosis and its GI symptoms.
  • Analysis of common gastrointestinal complaints associated with the disorder.

Related Experiment Videos

  • Identification of mast cell presence in related GI conditions.

    • Main Results:

    • Common GI symptoms include abdominal pain, diarrhea, nausea, vomiting, and gastrointestinal reflux disease.
    • Elevated mast cell counts are observed in patients with gastritis, ulcerative colitis, and Crohn's disease.
    • The high prevalence of GI issues underscores the systemic nature of mastocytosis.

    Conclusions:

    • Gastrointestinal symptoms are a major clinical feature of mastocytosis.
    • Awareness and recognition of these symptoms are crucial for timely diagnosis and management.
    • Gastroenterology nurses play a vital role in identifying and managing patients with mastocytosis-related GI complications.