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Updated: Feb 4, 2026

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
Published on: February 24, 2023
Melioidosis in Brunei Darussalam
Ketan Pande1, Khairul Azmi Abd Kadir2, Rosmonaliza Asli3
1Department of Orthopaedics, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan BG 1710, Negara Brunei Darussalam. ketanpande@yahoo.com.
Melioidosis remains a significant health issue in Brunei, with high mortality despite available treatments. Increased incidence during wet seasons and in Temburong highlights the need for public health interventions.
Area of Science:
- Infectious Diseases
- Public Health
- Epidemiology
Background:
- Melioidosis poses a substantial healthcare challenge in Brunei Darussalam.
- Disease characteristics in Brunei align with regional patterns.
Purpose of the Study:
- To analyze the epidemiology and clinical presentation of melioidosis in Brunei Darussalam.
- To identify factors associated with high mortality rates.
Main Methods:
- Retrospective analysis of melioidosis cases.
- Correlation of incidence with geographical location and rainfall patterns.
- Identification of demographic and clinical risk factors for mortality.
Main Results:
- High incidence observed during wet months and in the Temburong district.
- Overall mortality rate of 27%, with increased risk for women and septic shock patients.
- Clinical presentations and risk factors are consistent with regional data.
Conclusions:
- Melioidosis requires urgent public health attention in Brunei Darussalam.
- Consideration for making melioidosis a notifiable disease is recommended.
- Coordinated strategies are essential for effective disease control.
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