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Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
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Melioidosis in Myanmar.

Mo Mo Win1, Elizabeth A Ashley2,3, Khwar Nyo Zin4

  • 1Department of Medical Research, Yangon, Myanmar. drmomowin@gmail.com.

Tropical Medicine and Infectious Disease
|October 3, 2018
PubMed

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Summary
This summary is machine-generated.

Melioidosis, caused by Burkholderia pseudomallei, has been reported in Myanmar since 1911. Limited clinician awareness and diagnostic capacity likely result in significant under-reporting of this infectious disease.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Epidemiology

Background:

  • Melioidosis (caused by Burkholderia pseudomallei) has been documented in Myanmar since 1911.
  • Sporadic cases have been reported across seven states/regions, with a historical peak before 1949.

Purpose of the Study:

  • To summarize reported melioidosis cases in Myanmar.
  • To present findings from environmental and serosurveys.
  • To identify factors contributing to knowledge gaps in the disease's epidemiology.

Main Methods:

  • Review of published and unpublished melioidosis case reports (1911-2018).
  • Analysis of environmental soil surveys for Burkholderia pseudomallei.
  • Assessment of factors limiting disease surveillance and diagnosis.
Keywords:
Burkholderia pseudomalleiMyanmarmelioidosis

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Main Results:

  • A total of 298 melioidosis cases were identified between 1911 and 2018.
  • Burkholderia pseudomallei was detected in soil samples from all surveyed regions.
  • Lack of clinician awareness and inadequate laboratory capacity were identified as key issues.

Conclusions:

  • The true epidemiology of melioidosis in Myanmar remains largely unknown.
  • Under-reporting is likely substantial due to diagnostic and awareness challenges.
  • Further research and improved surveillance are needed to understand the disease burden.