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Onchodermatitis: Where Are We Now?

Michele E Murdoch1

  • 1Department of Dermatology, West Herts Hospitals NHS Trust, Vicarage Road, Watford, Hertfordshire WD18 0HB, UK. michele.murdoch@nhs.net.

Tropical Medicine and Infectious Disease
|October 3, 2018
PubMed
Summary
This summary is machine-generated.

Onchocerciasis, or river blindness, skin disease is declining globally due to mass drug distribution of ivermectin. This progress is leading to the elimination of onchocercal skin disease in many areas.

Keywords:
ivermectinonchocercal skin diseaseonchocerciasisonchodermatitis

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Area of Science:

  • Tropical medicine
  • Dermatology
  • Infectious diseases

Background:

  • Onchocerciasis causes severe skin conditions and blindness, historically prevalent in specific African regions.
  • Ivermectin mass drug administration is transforming the global onchocerciasis landscape.
  • The World Health Organization aims for African onchocerciasis elimination by 2025.

Purpose of the Study:

  • To review progress in understanding and treating onchocercal skin disease.
  • To assess the impact of control measures on onchodermatitis.
  • To highlight recent advancements in the past five years.

Main Methods:

  • Literature review of PubMed using keywords: 'onchocerciasis', 'onchodermatitis', 'onchocercal skin disease'.
  • Analysis of articles published within the last eight years, with English abstracts.
  • Inclusion of relevant references from assessed articles.

Main Results:

  • The global burden of onchodermatitis is decreasing.
  • Onchocercal skin disease is no longer observed in children in many former endemic areas.
  • Increased awareness, understanding, and treatment of onchocercal skin disease.

Conclusions:

  • Mass drug distribution of ivermectin is effectively reducing onchocerciasis.
  • Onchocercal skin disease is progressively being eliminated globally.
  • The target for onchocerciasis elimination in Africa by 2025 is supported by current progress.