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The Implementation Process for Pharmacogenomic Testing for Cancer-Targeted Therapies
Ann Chen Wu1, Kathleen M Mazor2, Rachel Ceccarelli3
1PRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Pilgrim Health Care Institute and Harvard Medical School, 401 Park Drive, Suite 401, Boston, MA 02215, USA. ann.wu@childrens.harvard.edu.
Journal of Personalized Medicine
|October 3, 2018
Summary
Ordering pharmacogenomic tests for cancer treatment is complex and time-consuming. The process for obtaining these genomic tests and securing insurance reimbursement varies significantly across healthcare institutions.
Area of Science:
- Genomic Medicine
- Clinical Diagnostics
- Health Services Research
Background:
- Genomic tests offer potential population health benefits.
- The process for ordering and insurance reimbursement of these tests is not well-described.
Purpose of the Study:
- To describe the process of ordering cancer-related pharmacogenomic tests.
- To identify logistical and insurance challenges in accessing these tests.
Main Methods:
- Interviews with 10 providers, 16 patients, and 8 diagnostic laboratories.
- Exploration of ordering and reimbursement issues for pharmacogenomic tests.
Main Results:
- Ordering pharmacogenomic tests is time-consuming, expensive, and complex.
- Processes vary significantly between and within institutions.
- Laboratories often initiate testing before confirming payment.
Conclusions:
- The ordering and insurance coverage processes for pharmacogenomic tests are highly variable and inefficient.
- Streamlining these processes is crucial for wider adoption and patient benefit.
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