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Updated: Feb 4, 2026

Investigations on the GaIII Complex of EOB-DTPA and Its 68Ga Radiolabeled Analogue
Published on: August 17, 2016
Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(iv)
Florian Lahrouch1, Bruno Siberchicot, Laurane Leost
1Université Côte d'Azur, CNRS, Institut de Chimie de Nice, UMR 7272, 06108 Nice, France. christophe.di-giorgio@unice.fr christophe.denauwer@unice.fr.
Abstract:
Up until now, molecular chelating agents, such as diethylenetriamine pentaacetic acid (DTPA), have been the standard method for actinide human decorporation. Mainly active in blood serum, their distribution within the body is thus limited. To treat a wider range of organs affected by plutonium contamination, a potential new class of macromolecular decorporation agents is being studied. Polyethyleneimine methylenecarboxylate (PEI-MC) is one such example. It is being considered here because of its capacity for targeting the liver and bones.
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