Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accessory Structures of the Skin: Nails01:05

Accessory Structures of the Skin: Nails

3.3K
Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
3.3K
Oxidation-Reduction Reactions03:11

Oxidation-Reduction Reactions

75.7K
Oxidation–Reduction Reactions
75.7K
Oxymercuration-Reduction of Alkenes02:36

Oxymercuration-Reduction of Alkenes

9.4K
Oxymercuration–reduction of alkenes is one of the major reactions converting alkenes to alcohols. It involves the hydration of alkenes with mercuric acetate in a mixture of tetrahydrofuran and water, forming an organomercury adduct. This is followed by a demercuration step in which the adduct is reduced to an alcohol using sodium borohydride.
9.4K
Block Diagram Reduction01:22

Block Diagram Reduction

567
The process of deriving the transfer function of a control system often involves reducing its block diagram to a single block. This simplification can be achieved through a series of strategic operations, including relocating branch points and comparators. These operations preserve the overall function of the system while allowing for easier manipulation and combination of blocks.
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
567
Phase I Reactions: Reductive Reactions01:27

Phase I Reactions: Reductive Reactions

597
Phase I biotransformation reductive reactions are chemical processes that modify drugs by introducing or revealing polar functional groups via reduction. Enzymes called reductases catalyze these reactions, playing a pivotal role in drug metabolism by transforming lipophilic drugs into more polar, water-soluble metabolites for easy excretion. An essential type of reductive reaction is the carbonyl group reduction, where aldehydes and ketones are reduced to alcohols. An example is the...
597
Esters to Alcohols: Hydride Reductions01:17

Esters to Alcohols: Hydride Reductions

4.8K
Esters are reduced to primary alcohols when treated with a strong reducing agent like lithium aluminum hydride. The reaction requires two equivalents of the reducing agent and proceeds via an aldehyde intermediate.
Lithium aluminum hydride is a source of hydride ions and functions as a nucleophile. The mechanism proceeds in three steps. Firstly, the nucleophilic hydride ion attacks the carbonyl carbon of the ester to form a tetrahedral intermediate. Subsequently, the carbonyl group re-forms,...
4.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Incorporating the concept of overtransfusion into hemovigilance monitoring: An expert-based definition and criteria from the International HIT-OVER Forum.

Transfusion·2024
Same author

Towards international collaboration of clinical research networks for EMDR: the EMDR Pain Network Germany.

Frontiers in psychology·2024
Same author

Three-year follow-up analysis of the short-stitch versus long-stitch technique for elective midline abdominal closure randomized-controlled (ESTOIH) trial.

Hernia : the journal of hernias and abdominal wall surgery·2024
Same author

Management of perioperative iron deficiency anemia as part of patient blood management in France: A budget impact model-based analysis based on real world data.

Transfusion·2023
Same author

[Trampolining-induced gross hematuria : Unmasking the nutcracker syndrome].

Urologie (Heidelberg, Germany)·2022
Same author

[Atypical femoral fracture : Pitfalls in surgical treatment].

Unfallchirurgie (Heidelberg, Germany)·2022
Same journal

[3D printing in fracture treatment : Current practice and best practice consensus].

Der Unfallchirurg·2022
Same journal

[3D printing in trauma surgery : Germany lags far behind].

Der Unfallchirurg·2022
Same journal

[Subtrochanteric fractures].

Der Unfallchirurg·2022
Same journal

[3D printing in the field of shoulder surgery].

Der Unfallchirurg·2022
Same journal

[New assessment recommendations for disability in private accident insurance, part 1 : An interdisciplinary consented approach-Basics].

Der Unfallchirurg·2022
Same journal

[Amputation techniques].

Der Unfallchirurg·2022
See all related articles

Related Experiment Video

Updated: Feb 4, 2026

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
04:41

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Published on: June 6, 2025

1.1K

[Reduction techniques in intramedullary nailing osteosynthesis].

P M Rommens1, R Kuechle2, A Hofmann3

  • 1Zentrum für Orthopädie und Unfallchirurgie, Universitätsmedizin der Johannes Gutenberg-Universität, Langenbeckstr. 1, 55131, Mainz, Deutschland. pol.rommens@unimedizin-mainz.de.

Der Unfallchirurg
|October 3, 2018
PubMed
Summary
This summary is machine-generated.

Intramedullary nailing stabilizes long bone shaft fractures. Advanced techniques and interlocking screws enhance fracture reduction and fixation, improving operative outcomes for complex cases.

Keywords:
FracturesInterlockingIntramedullary nailingMetaphysisReduction

More Related Videos

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

13.9K
Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
06:38

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Published on: October 12, 2016

10.5K

Related Experiment Videos

Last Updated: Feb 4, 2026

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
04:41

Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner

Published on: June 6, 2025

1.1K
An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
07:41

An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice

Published on: November 13, 2016

13.9K
Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis
06:38

Establishment of a Segmental Femoral Critical-size Defect Model in Mice Stabilized by Plate Osteosynthesis

Published on: October 12, 2016

10.5K

Area of Science:

  • Orthopedic Surgery
  • Biomedical Engineering

Background:

  • Intramedullary nailing is a standard for long bone shaft fractures.
  • Evolving nail designs and interlocking options expand its application.
  • Fractures beyond the isthmus present reduction challenges.

Purpose of the Study:

  • To review advanced techniques for intramedullary nailing of complex fractures.
  • To highlight methods for fracture reduction and optimal nail placement.
  • To discuss the role of blocking screws and interlocking in achieving stable fixation.

Main Methods:

  • Review of indirect reduction techniques (extension table, distractors, external fixators).
  • Discussion of direct reduction adjuncts (forceps, lag screws, cerclage, plates).
  • Analysis of optimal entry portal selection and blocking screw utilization.

Main Results:

  • Indirect and direct reduction methods optimize fracture alignment.
  • Correct entry portal selection is crucial for surgical success.
  • Blocking screws prevent malalignment and guide wire placement.
  • Suprapatellar approach allows nail insertion without stressing fragments.
  • Interlocking prevents secondary dislocation and ensures stability.

Conclusions:

  • Advanced intramedullary nailing techniques improve outcomes for complex fractures.
  • Precise fracture reduction and optimal nail insertion are key.
  • Blocking screws and interlocking fixation enhance stability and prevent complications.