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Updated: Feb 4, 2026

Zebrafish Corneal Wound Healing: From Abrasion to Wound Closure Imaging Analysis
Published on: March 1, 2022
[PLASTIC CLOSURE OF THE WOUND DEFECT IN PATIENTS, SUFFERING THE ORAL AND ORO-PHARYNGEAL CANCER STAGES ІІІ - ІV]
Abstract:
Results of treatment of 124 patients, suffering locally-advanced oral and oropharyngeal cancer were analyzed. In these patients after wide excision of tissues the defect has occurred, which would be impossible to close using simple suturing. To these patients a primary plasty, using musculo-cutaneous or adiposo-cutaneous flap, was performed. The defect, occurring after resection of the oral cavity floor together with the mandibular anterior fragment, constitutes the most complex one for the plasty performance. The main principles of the defects plasty were determined. The plastic material choice depends on peculiar clinical situation, the surgical intervention volume, the defect localization and its size.
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