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Related Experiment Videos

Itraconazole in pityriasis versicolor.

R A Estrada

    Reviews of Infectious Diseases
    |January 1, 1987
    PubMed
    Summary

    Itraconazole effectively treated pityriasis versicolor in most patients. A higher dose (200 mg/day) showed a trend towards better cure rates than a lower dose (100 mg/day) over 30 days.

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    Area of Science:

    • Dermatology
    • Mycology

    Background:

    • Pityriasis versicolor is a common superficial fungal infection.
    • Itraconazole is an antifungal medication used to treat various fungal infections.

    Purpose of the Study:

    • To evaluate the efficacy of two different daily dosages of itraconazole in treating pityriasis versicolor.
    • To compare the cure rates between patients receiving 200 mg/day and 100 mg/day of itraconazole.

    Main Methods:

    • A randomized study involving 42 patients with pityriasis versicolor.
    • Two treatment groups: 200 mg itraconazole daily for 5 days vs. 100 mg daily for 5 days.
    • Clinical evaluation, Wood's light examination, and direct microscopic examination were used to assess treatment outcomes over 30 days.

    Main Results:

    • The cure rate was 95% in the group receiving 200 mg/day and 75% in the group receiving 100 mg/day.
    • While not statistically significant due to small group sizes, a higher cure rate was observed with the 200 mg/day dosage.
    • Itraconazole demonstrated high efficacy in treating pityriasis versicolor.

    Conclusions:

    • Itraconazole is an effective treatment for pityriasis versicolor.
    • The 200 mg/day dosage may offer a higher cure rate compared to 100 mg/day, warranting further investigation.
    • Further studies with larger cohorts are needed to confirm dosage-dependent efficacy.

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