Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ion Channels01:19

Ion Channels

91.5K
The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
91.5K
Non-gated Ion Channels01:24

Non-gated Ion Channels

8.3K
Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism....
8.3K
Parabolas01:30

Parabolas

321
A parabola is a fundamental curve in the family of conic sections arising from the intersection of a plane with a double-napped cone when the plane is parallel to the cone’s slant height. This geometric condition yields a unique open curve defined by its equidistance from a fixed point, the focus, and a fixed line, the directrix.A parabola is mathematically defined as the locus of all points in a plane that are equidistant from the focus and the directrix. In Cartesian coordinates, the...
321
Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

7.8K
Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
7.8K
Ligand-gated Ion Channels01:19

Ligand-gated Ion Channels

14.4K
Ligand-gated ion channels are transmembrane proteins with a channel for ions to pass through and a binding site for a ligand. The channel opens only when a ligand attaches to the binding site.
Three Subfamilies of Ligand-gated Ion Channels
Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that...
14.4K
G-Protein Gated Ion Channels01:21

G-Protein Gated Ion Channels

5.7K
GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
Sensory...
5.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CuO(200)-CuO(1Ì…11) Interface Enables Efficient Low-Temperature Catalytic Decomposition of CH<sub>3</sub>SH.

ACS applied materials & interfaces·2026
Same author

Unified multimodal learning for stroke triage: joint detection, scoring, and segmentation of acute ischemic stroke.

NPJ digital medicine·2026
Same author

Mechanical and oral antibiotics bowel preparation reduce the risk of surgical site infections and anastomotic leakage in colorectal surgery: a GRADE-based meta-analysis and trial sequential analysis.

Frontiers in medicine·2026
Same author

Dietary one‑carbon nutrients and genetic risk in Parkinson disease: a prospective cohort study.

The journals of gerontology. Series A, Biological sciences and medical sciences·2026
Same author

The safety and efficacy of low pneumoperitoneum pressure compared with standard pneumoperitoneum pressure in laparoscopic inguinal hernia repair: a prospective, double-blind, randomized controlled study protocol design.

Trials·2026
Same author

Genomic signature driving preinvasive to invasive processes in stage I lung adenocarcinoma.

International journal of cancer·2025

Related Experiment Video

Updated: Feb 4, 2026

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
08:40

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

Published on: January 20, 2022

4.9K

An angular-resolved multi-channel Thomson parabola spectrometer for laser-driven ion measurement.

Yihang Zhang1, Zhe Zhang1, Baojun Zhu1

  • 1Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China.

The Review of Scientific Instruments
|October 4, 2018
PubMed
Summary

A novel multi-channel Thomson parabola spectrometer diagnoses ion beams from intense laser pulses. This compact device provides angular-resolved energy spectra for comprehensive ion beam characterization in a single shot.

More Related Videos

Direct Imaging of Laser-driven Ultrafast Molecular Rotation
10:52

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Published on: February 4, 2017

10.2K
Dithranol as a Matrix for Matrix Assisted Laser Desorption/Ionization Imaging on a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer
09:38

Dithranol as a Matrix for Matrix Assisted Laser Desorption/Ionization Imaging on a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

Published on: November 26, 2013

14.6K

Related Experiment Videos

Last Updated: Feb 4, 2026

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments
08:40

Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

Published on: January 20, 2022

4.9K
Direct Imaging of Laser-driven Ultrafast Molecular Rotation
10:52

Direct Imaging of Laser-driven Ultrafast Molecular Rotation

Published on: February 4, 2017

10.2K
Dithranol as a Matrix for Matrix Assisted Laser Desorption/Ionization Imaging on a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer
09:38

Dithranol as a Matrix for Matrix Assisted Laser Desorption/Ionization Imaging on a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer

Published on: November 26, 2013

14.6K

Area of Science:

  • Plasma Physics
  • Laser-driven Ion Acceleration
  • Spectroscopy

Background:

  • Diagnosing ion beams generated by intense laser pulses is crucial for understanding laser-plasma interactions.
  • Existing methods may lack the resolution or capability for comprehensive, single-shot analysis.

Purpose of the Study:

  • To design and validate a multi-channel Thomson parabola spectrometer for diagnosing laser-driven ion beams.
  • To enable simultaneous measurement of angular-resolved energy spectra for multiple ion species.

Main Methods:

  • A multi-channel Thomson parabola spectrometer incorporating parallel dipole magnets and wedged electrodes was designed.
  • Entrance pinhole channel dimensions were optimized for resolution and to prevent beam overlap.
  • Three-dimensional electric and magnetic field distributions were simulated for precise energy spectral resolving.

Main Results:

  • The spectrometer successfully measured angular-resolved energy spectra of protons and deuterons in a single shot.
  • The design demonstrated effective ion dispersion for various charge-to-mass ratios.
  • Comprehensive characterization of laser-driven ion beams was achieved.

Conclusions:

  • The developed multi-channel Thomson parabola spectrometer offers a compact and effective solution for ion beam diagnostics.
  • This instrument facilitates detailed analysis of ion beams produced by intense laser pulses.
  • The design advances the capability for studying laser-plasma acceleration mechanisms.