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Published on: March 31, 2023
Enterobacter Meningitis Due To Dermoid Cyst Manipulation
Sedigheh Rafiei Tabatabei1, Roxana Azma2, Manijeh Kahbazi3
1Pediatric Infections Research Center, Research Institute for Children Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract:
Gram-negative meningitis can occurssubsequent to dura-arachnoid barrier disruption because of trauma, surgery and rarely an infected dermoid cyst. Association of neurosurgical procedures with Gram-negative meningitis was described for the first time in 1940. Intracranial infections from gram-negative bacilli like Enterobacter are serious and difficult to treat as many antibiotics fail to achieve bactericidal concentrations in the cerebrospinal fluid. Here in, we report a rare case of pediatric Enterobacter meningitis in a patient with a dermoid cyst that had been manipulated. She was managed with antibiotic therapy plus surgical removal of the infected cyst.
Insights
Pediatric Gram-negative meningitis, particularly Enterobacter meningitis, is rare but serious following dura-arachnoid barrier disruption. This case highlights successful management via antibiotics and surgical cyst removal.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Gram-negative meningitis can arise after disruption of the dura-arachnoid barrier due to trauma, surgery, or infected dermoid cysts.
- Intracranial infections caused by gram-negative bacilli, such as Enterobacter, pose significant treatment challenges due to poor antibiotic penetration into cerebrospinal fluid.
Observation:
- A rare case of pediatric Enterobacter meningitis is presented in a patient with a history of a manipulated dermoid cyst.
- The patient presented with symptoms indicative of meningitis secondary to the cyst.
Findings:
- The patient was successfully treated with a combination of antibiotic therapy and surgical excision of the infected dermoid cyst.
- This approach effectively resolved the Enterobacter meningitis.
Implications:
- This case underscores the importance of considering infected dermoid cysts as a potential cause of Gram-negative meningitis in pediatric patients.
- Combined antibiotic and surgical management can be highly effective in treating such complex intracranial infections.
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