Coronary artery stenting in acute coronary syndrome associated with giant cell arteritis
Lillian Armellin1, Anthony Michael Sammel2, Ben Ng1
1Prince of Wales Clinical School, University of New South Wales, Sydney, Australia.
Insights
Giant cell arteritis can affect coronary arteries, a rare complication. Treatment may involve immunosuppression and drug-eluting stents for this serious condition.
Area of Science:
- Cardiovascular Medicine
- Rheumatology
- Pathology
Background:
- Giant cell arteritis (GCA), or temporal arteritis, is a large vessel vasculitis.
- While typically affecting cranial and aorta arteries, GCA can involve medium and large arteries systemically.
Observation:
- Two cases of GCA involving the coronary arteries are presented.
- One case was identified post-mortem, while the other received successful treatment.
Findings:
- Coronary vasculitis is a rare but severe manifestation of GCA.
- Successful treatment involved immunosuppressive therapy and drug-eluting coronary stents.
Implications:
- Clinicians should consider GCA in patients with atypical coronary artery disease presentations.
- Drug-eluting stents offer a potential therapeutic option for coronary vasculitis in GCA.
Abstract:
Coronary vasculitis is a rare but devastating complication of giant cell arteritis, otherwise known as temporal arteritis. Originally named for its propensity to attack the superficial temporal arteries, it is now recognized that it commonly involves a number of medium and large arteries throughout the body. Here we describe two cases of giant cell arteritis affecting the coronary arteries, one discovered at post-mortem and one which was successfully treated with immunosuppressive therapy and drug-eluting coronary stents. <Learning objective: Giant cell arteritis is a large vessel vasculitis which commonly affects the superficial temporal, subclavian arteries, and aorta but in rare cases can involve the coronary arteries. In addition to standard corticosteroid therapy, drug-eluting stents may be useful in treating this rare but serious disease. Clinicians should both consider this condition in patients with atypical features of coronary artery disease and recognize drug-eluting stents as a potential effective therapy.>.
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