Related Experiment Video
Updated: Feb 4, 2026

Comparative Lesions Analysis Through a Targeted Sequencing Approach
Published on: November 5, 2019
Support with a twist: New approaches in CTOs and complex lesions
1University of Arizona College of Medicine, Phoenix, AZ, USA.
Abstract:
One-third of patients undergoing coronary angiography have coronary chronic total occlusions (CTOs) with the incidence increasing with age. Successful recanalization of a CTO is associated with a reduction in the future need for coronary artery bypass graft surgery (CABG), improvement in left ventricular function, and angina status as well as long-term survival. Success rates for treating CTOs with conventional techniques have remained unchanged over time averaging 65%-70% in experienced hands, well below the success rates for non-occlusive coronary lesions. The antegrade approach is utilized in standard balloon angioplasty. Modification of this technique has been used with an anchoring balloon to more successfully open up CTOs. We describe a new device that in addition to allowing increased support, also centers one in the lumen for both coronary and peripheral intervention.
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