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Updated: Feb 4, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Long-standing persistent effects of atrial volume reduction combined with pulmonary vein isolation
Masami Takagaki1, Naoko Ikeda2, Hiroki Yamaguchi1
1Department of Cardiovascular Surgery, Showa University Koto Toyosu Hospital, Tokyo, Japan.
Abstract:
Although surgical left atrial (LA) volume reduction combined with mitral valve surgery and/or surgical ablation for atrial fibrillation has been reported to be effective, its long-term outcomes in the absence of mitral procedure are not well established. A 74-year-old man with two previous sternotomies-the first for pericardiectomy due to constrictive pericarditis and the second for mitral valve replacement with mechanical valve and tricuspid annuloplasty-presented with heart failure and thrombus in his giant left atrium (1291 mL), complicated by cerebral infarction. His electrocardiogram showed rate-controlled persistent atrial fibrillation. His mechanical valve was functioning well. A third atrial volume reduction combined with pulmonary vein isolation, without valve surgery, was performed. The postoperative course was uneventful, and the patient has remained asymptomatic with regular junctional rhythm and without any episodes of thromboembolism or re-dilation of LA (approximately 550 mL). His left ventricular filling improved with end-diastolic volume (96 mL vs 140 mL) and forced vital capacity (2.60 L vs 2.89 L) increased. Both remained relatively constant for 6 years. The combination of atrial volume reduction with pulmonary vein isolation prevented thromboembolism, improved left ventricular filling, and continued to improve symptoms associated with heart failure and respiratory condition for 6 years. <Learning objective: The long-term outcomes of surgical left atrial volume reduction combined with ablation for atrial fibrillation in the absence of mitral valve procedure are not well established. We hereby report a case of left atrial volume reduction combined with pulmonary vein isolation, without valve surgery, whose beneficial effects on symptoms associated with heart failure, particularly left ventricular filling, respiratory function, and stroke prevention, have persisted for 6 years postoperatively.>.
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